Hyalase, also known as hyaluronidase, is an enzyme used as a filler dissolver in cosmetic procedures that is employed to break down and dissolve hyaluronic acid-based dermal fillers that have been previously injected into the skin. A filler dissolver is used when patients desire an adjustment or reversal of the filler effects, or complications arise due to overfilling or asymmetry.

It works by breaking down the hyaluronic acid molecules in the filler, allowing the body’s natural processes to absorb and metabolize the material. This enzyme helps to expedite the process of reversing the effects of dermal fillers, restoring the treated area to its pre-filler state.


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What To Expect

Frequently Asked Questions

How long does the filler dissolver take to dissolve?

Immediately after the injections, your filler will begin breaking down and softening, although seeing your filler completely dissolve may take up to two weeks. This can vary between clients based on the location of the filler and the amount of filler to be dissolved.

How many treatments will I need to dissolve my filler?

Clients should know that achieving desired corrections might involve multiple treatments over time. The number of sessions can vary based on filler type, the volume of dermal filler injected, and the length of time the filler has been present. Older, larger volumes of filler could require three to four sessions, spaced over two weeks, for full resolution, while most cases achieve desired results in one or two sessions.

Can all dermal fillers be dissolved?

Not all dermal fillers can be dissolved. The dissolving agent is effective only on temporary fillers composed of natural substances commonly used for cheek and lip augmentation. However, this method cannot reverse semi-permanent fillers like collagen stimulations.

Will it dissolve my natural hyaluronic acid?

This is a common concern when discussing the dissolving process. The enzyme used to dissolve filler can affect both natural and injected hyaluronic acid. However, our skin’s natural hyaluronic acid replenishes quickly, with a half-life of around 24 hours, so any natural hyaluronic acid dissolved is rapidly corrected.

What is recovery like?

Aftercare for filler dissolver involves a short recovery period with initial swelling, lasting around 24 to 48 hours in areas like lips and under the eyes. Once the swelling subsides, the volume loss from dissolved filler becomes evident, often with immediate improvements. Some areas may have temporary skin laxity due to puffy or misplaced filler. Other post-injection effects can include mild to moderate redness, swelling, pain, itching, bruising and tenderness, typically resolving within a few days. It is important to adhere to specific aftercare instructions for a smooth and successful recovery.

What is used as a filler dissolver?

Hyalase, or hyaluronidase, is an enzyme used as a filler dissolver in cosmetic procedures to break down and dissolve hyaluronic acid-based dermal fillers.

How does filler dissolver work?

The filler dissolver breaks down the hyaluronic acid molecules in the filler, allowing the body’s natural processes to absorb and metabolise the material.

Will this work if my filler has moved?

If you’ve experienced a displaced or migrated filler, dissolving the filler is the best solution. The filler dissolver is injected precisely into the area where the dermal filler has migrated and works quickly once injected. Most of the effects occur within 24 hours of the procedure, with the dissolving results taking up to seven days to be completely visible.

Doesn’t filler dissolve naturally over time?

While it is true that some fillers dissolve and are discarded by the body, fillers made of hyaluronic acid must have a source of hyaluronidase to break them down. This means that for your filler to dissolve, your body must produce a regular source of hyaluronidase at the injection site over a prolonged period. Your body does not want to regularly produce hyaluronidase because this would cause your skin and other organs to break down.

Does dissolving filler hurt?

Hyaluronidase (or hyalase) can sting significantly on injection. However, we use an anaesthetic mixed with the injection to remove any sting from the injection. Also, a topical anesthetic may be used if multiple injections are required, but most clients feel the treatment is comfortable.

Before & After